Nos tutelles





Accueil > Membres > Les membres > Annuaire

Perrier Lionel

Address : Centre de Lutte Contre le Cancer Léon Bérard
Direction de la Recherche Clinique et de l’Innovation (DRCI)
28 rue Laënnec 69008 Lyon, France
Phone :+33 4 78 78 29 08 / Assistante +33 4 69 85 61 00
Fax :+33 4 78 78 59 45


Current position

  • in charge of the Innovations and strategies Unit, Clinical research and innovation direction (DRCI), Cancer Centre Léon Bérard, Lyon, France
  • Member of the Commission for Economic Evaluation and Public Health (CEESP), French National Authority for Health (HAS)
  • Lecturer (Lyon 2 University and Ecole Centrale de Lyon)
  • Hospinnomics chair associate researcher (Paris School of Economics, Assistance Publique - Hôpitaux de Paris)


  • Habilitation (HDR), Lyon 2 University, 2010
  • PhD in Economics, Lyon 2 University, 2001

Fields of interest

  • Health Technology Assessment
  • Health care systems and reforms
  • Quality of life

Teaching and students

Teaching 2017-2018

  • Master RisE – Risques et Environnement, Ecole Centrale de Lyon
  • Master Analyse et Politiques Economiques, Lyon 2 University

PhD thesis supervision

  • Wilfried Guets, Modélisation de l’aide informelle : approches économiques et applications au dispositif innovant d’accompagnement et de répit des aidants de la métropole de Lyon, Lyon 2 University (since 2017)
  • Marius Huguet, Traitement du biais de sélection, estimation de l’effet causal et modélisation microéconomique : une application à la prise en charge des cancers de l’ovaire en France (co-supervision with X. Joutard, Aix Marseille University), Lyon 2 University (since 2016)
  • Noémie Defourny, The cost of Radiotherapy in Europe : what does it cost, and how can these data be used to support innovation in European radiotherapy practice ? (co-supervision with Y. Lievens University of Gent), University of Gent, Belgium (since 2014)
  • Maria Laura Silva, The role of the economic evaluations in health decision making : an application to influenza vaccination, Lyon 2 University (date of Defense 7th March 2016) ; Associate Professor, University of Bordeaux

Participation as referee / external examiner to PhD theses’ defense

  • Omar Kanj, University Clermont Auvergne, 2017 (referee)
  • Sabri Hamana, Modélisation et simulation des flux d’informations ville-hôpital et de leur impact sur le parcours de soins, Ecole Nationale des Mines de Saint-Etienne, 2017 (external examiner)

Other responsabilities

Research programm coodinator

  • Coodinator (with H. Serrier and X. Xie) Evaluation of the very high sequencing platform built by the AURAGEN Consortium, AAP Mise en oeuvre et l’évaluation de projets pilotes de plateformes de séquençage très haut débit à visée sanitaire, Ministry of Health (DGOS), 2017
  • Coordinator Modélisation de l’aide informelle : approches économiques et applications au dispositif innovant d’accompagnement et de répit des aidants de la métropole de Lyon, AAP Handicap et perte d’autonomie, session 7 (IRESP), 2016
  • Coodinator (with R. de Crevoisier) Erectile dysfunction in low-risk prostate cancer : a phase III medico-economic study comparing brachytherapy to stereotactic body radiotherapy, PRME-K, French National Cancer Institute (INCa), 2016
  • Coodinator (with Sébastien Thureau) Economic evaluation of Extracranial stereotactic Body Radiation Therapy (SBRT) added to standard treatment versus standard treatment alone in solid tumors patients with ≤3 bone-only metastasis, PHRC-K, French National Cancer Institute (INCa), 2015
  • Coodinator (with R. de Crevoisier), Health economics evaluation of the adaptive radiotherapy strategy to decrease xerostomia in locally advanced oropharynx carcinoma, PRME-K, French National Cancer Institute (INCa), 2014
  • Coodinator (with I. Ray Coquard), Optimisation of disease management in patients with epithelial ovarian/fallopian tube/primary peritoneal carcinoma in France, PRME-K, French National Cancer Institute (INCa), 2014
  • Coordinator (with S. Baffert, I. Borget, I. Durand Zaleski, P.Marino), Economic impact of Next-generation sequencing (NGS) technologies, French National Cancer Institute (INCa), 2014
  • Coordinator Health information system evaluation, AAP PREPS SIPS, Ministry of Health, 2013
  • Coordinator (with JM Coindre) Economic evaluation of a second opinion in sarcoma, GIST, and desmoid tumour treatments , French National Cancer Institute (INCa), 2012

Expertise and other collective responsabilities

  • Member of the selection committee for grants “Programme de Recherche Médico-Economique (PRME-N)”, French Ministry of Health (since 2013)
  • Member of the Steering Committee GT 4 Innovation, French National Committee of the clinical research and innovation (Assemblée nationale des délégations à la recherche clinique et à l’innovation), since 2012
  • Member of the Abstract Review Committee for the ISPOR International Meetings

Last publications

  • Gnep K, Lizée T, Campillo-Gimenez B, Delpon G, Droupy S, Perrier L, de Crevoisier R. Toxicity and quality of life comparison of iodine 125 brachytherapy and stereotactic radiotherapy for prostate cancers. Cancer Radiother. 2017 Oct ;21(6-7):478-490. doi : 10.1016/j.canrad.2017.07.043
  • Bibault JE, Dussart S, Pommier P, Morelle M, Huguet M, Boisselier P, Coche-Dequeant B, Alfonsi M, Bardet E, Rives M, Calugaru V, Chajon E, Noel G, Mecellem H, Servagi Vernat S, Perrier L, Giraud P. Clinical Outcomes of Several IMRT Techniques for Patients With Head and Neck Cancer : A Propensity Score-Weighted Analysis. Int J Radiat Oncol Biol Phys. 2017 Jun 27. pii : S0360-3016(17)33522-8. doi : 10.1016/j.ijrobp.2017.06.2456
  • Penel-Page M, Marec-Bérard P, Morelle M, Bertrand A, Riberon C, Boyle H, Perrier L. Management of Febrile Neutropenias in Adolescents and Young Adults : A Cost-Minimization Analysis Between Adult Versus Pediatric Units. J Adolesc Young Adult Oncol. 2017 Jul 5. doi : 10.1089/jayao.2017.0035
  • Rejeb O, Pilet C, Hamana S, Xie X, Durand T, Aloui S, Doly A, Biron P, Perrier L, Augusto V. Performance and cost evaluation of health information systems using micro-costing and discrete-event simulation. Health Care Manag Sci. 2017 May 17. doi : 10.1007/s10729-017-9402-x
  • Plantier M, Havet N, Durand T, Caquot N, Amaz C, Biron P, Philip I, Perrier L. Does adoption of electronic health records improve the quality of care management in France ? Results from the French e-SI (PREPS-SIPS) study. Int J Med Inform. 2017 Jun ;102:156-165. doi : 10.1016/j.ijmedinf.2017.04.002
  • Varin M, Charbotel B, Pérol O, Perrier L, Massardier-Pilonchéry A, Bonnand S, Belladame E, Fort E, Avrillon V, Rebattu P, Pérol M, Fervers B. Assessment of a self-administered questionnaire identifying occupational exposures among lung cancer patients. Bull Cancer. 2017 Jun ;104(6):559-564. doi : 10.1016/j.bulcan.2017.03.014
  • Havet N, Penot A, Morelle M, Perrier L, Charbotel B, Fervers B. Trends in occupational disparities for exposure to carcinogenic, mutagenic and reprotoxic chemicals in France 2003-10.Eur J Public Health. 2017 Jun 1 ;27(3):425-432. doi : 10.1093/eurpub/ckx036
  • Sambou C, Guillemaut S, Morelle M, Achache A, Le Corroller AG, Perol D, Perrier L. ISO 9001 certification of innovation and clinical research departments : Extending the scope of health assessment. Rev Epidemiol Sante Publique. 2017 Apr ;65(2):159-167. doi : 10.1016/j.respe.2016.12.026
  • Havet N, Penot A, Morelle M, Perrier L, Charbotel B, Fervers B. Varied exposure to carcinogenic, mutagenic, and reprotoxic (CMR) chemicals in occupational settings in France. Int Arch Occup Environ Health. 2017 Feb ;90(2):227-241
  • Plantier M, Havet N, Durand T, Caquot N, Amaz C, Philip I, Biron P, Perrier L. Does adoption of electronic health records improve organizational performances of hospital surgical units ? Results from the French e-SI (PREPS-SIPS) study. Int J Med Inform. 2017 Feb ;98:47-55. doi : 10.1016/j.ijmedinf.2016.12.002
  • Perrier L, Morelle M, Huguet M, Dussart S, Giraud P. In Reply to Escande et al. Int J Radiat Oncol Biol Phys. 2017 Jan 1 ;97(1):205-208
  • Ceraulo A, Ouziel A, Lavergne E, Perrier L, Decouvelaere AV, Chotel F, Thiesse P, Marec-Berard P. Percutaneous guided biopsy for diagnosing suspected primary malignant bone tumors in pediatric patients : a safe, accurate, and cost-saving procedure. Pediatr Radiol. 2017 Feb ;47(2):235-244. doi : 10.1007/s00247-016-3735-3