Lionel Perrier
Manager Ph.D., H.D.R., Innovations and strategies Unit, Leon Berard Cancer Centre (Centre Léon Bérard)
I received the Ph.D. degree in economics and the Habilitation Diriger des Recherches degree from the University of Lyon, Lyon, France, in 2002 and 2010, respectively. I am currently responsible for the innovations and strategies unit in the Clinical Research Direction of the Léon Bérard Cancer Centre, Lyon. I am a member of the Economic and Public Health Evaluation Committee (CEESP), French National Authority for Health (HAS). I am also with the Ethics Focus Group, Léon Bérard Cancer. As a scientific coordinator, a work package leader or scientist, I am in charge of the health economist part of numerous projects and solicited for teaching in this field amongst other in Emlyon Lyon Business School and École Centrale de Lyon.
ONGOING RESEARCH ▼
- A multidisciplinary Data-driven approach for care pathway Optimization of non-elective SurgEry patients, ANR-funded DOSE project 2024
- UPright radiotherapy: Learning, Innovation, Fellowship and Training. HORIZON-MSCA-2023-DN-01
- Preoperative localisation of nonpalpable breast lesions using magnetic markers: a French health-economic study, Ministry of Health (DGOS), research project PRME 2022
- Impact of a multidisciplinary assessment of supportive care in day hospital versus standard care in patients at the end of initial treatment for gynaecological ovarian and endometrial cancer, Ministry of Health (DGOS), research project PREPS 2022
- Evaluation of the genome sequencing platforms Auragen and SeqOIA, Ministry of Health (DGOS), research project Plan France Médecine Génomique 2025
- Optimization of sarcoma patients’ pathway in France, Ministry of Health (DGOS), research project PRME 2018
- The role of zoledronic acid in the management of vertebral metastases by stereotactic radiotherapy, Ministry of Health (DGOS), research project PRME 2017
PUBLICATIONS ▼
Gisele Chvetzoff, Amélie Anota, Lionel Perrier, Julien Gautier, Carole Bouleuc, et al.. Systematic referral to palliative care in patients attending dedicated emergency units from French comprehensive anticancer centres: the prospective multicentre randomised comparative clinical trial PALLU. BMJ Open, 2025, 15 (8), pp.e101299. ⟨10.1136/bmjopen-2025-101299⟩. ⟨hal-05353857⟩
Lionel Perrier, Frederic Balusson, Magali Morelle, Joël Castelli, Juliette Thariat, et al.. Cost-effectiveness of weekly adaptive radiotherapy versus standard IMRT in head and neck cancer alongside the ARTIX trial. Radiotherapy & Oncology, 2024, Radiotherapy and Oncology : Journal of the European Society For Therapeutic, 193, pp.110116. ⟨10.1016/j.radonc.2024.110116⟩. ⟨hal-04444231⟩
Zhihao Peng, Vincent Augusto, Lionel Perrier, Xiaolan Xie. Optimal Process Mining of Traces With Events and Transition Attributes With Application to Care Pathways of Cancer Patients. IEEE Transactions on Automation Science and Engineering, 2023, pp.1-18. ⟨10.1109/TASE.2023.3295947⟩. ⟨hal-04169012⟩
Marina Touillaud, Baptiste Fournier, Olivia Pérol, Lidia Delrieu, Aurélia Maire, et al.. Connected device and therapeutic patient education to promote physical activity among women with localised breast cancer (DISCO trial): protocol for a multicentre 2×2 factorial randomised controlled trial. BMJ Open, 2023, 11, pp.e045448. ⟨10.1136/bmjopen-2020-045448⟩. ⟨halshs-03428061⟩
Marius Huguet, Marianne Sarazin, Lionel Perrier, Vincent Augusto. How We Can Reap the Full Benefit of Teleconsultations: Economic Evaluation Combined With a Performance Evaluation Through a Discrete-Event Simulation. Journal of Medical Internet Research, 2022, 24 (5), pp.e32002. ⟨10.2196/32002⟩. ⟨hal-03846527⟩
Marius Huguet, Xavier Joutard, Isabelle Ray-Coquard, Lionel Perrier. What underlies the observed hospital volume- outcome relationship?. BMC Health Services Research, 2022, 22 (70), ⟨10.1186/s12913-021-07449-2⟩. ⟨halshs-01801598⟩
Sébastien Thureau, Vincent Marchesi, Marie-Hélène Vieillard, Lionel Perrier, Albert Lisbona, et al.. Efficacy of extracranial stereotactic body radiation therapy (SBRT) added to standard treatment in patients with solid tumors (breast, prostate and non-small cell lung cancer) with up to 3 bone-only metastases: study protocol for a randomised phase III trial (STEREO-OS). BMC Cancer, 2021, 21 (1), pp.117. ⟨10.1186/s12885-021-07828-2⟩. ⟨hal-03226371⟩
Sébastien Thureau, Vincent Marchesi, Marie-Hélène Vieillard, Lionel Perrier, Albert Lisbona, et al.. Efficacy of extracranial stereotactic body radiation therapy (SBRT) added to standard treatment in patients with solid tumors (breast, prostate and non-small cell lung cancer) with up to 3 bone-only metastases: study protocol for a randomised phase III trial (STEREO-OS). BMC Cancer, 2021, 21 (1), ⟨10.1186/s12885-021-07828-2⟩. ⟨halshs-03428060⟩
François Gernier, Djihane Ahmed-Lecheheb, Patricia Pautier, Anne Floquet, Cédric Nadeau, et al.. “Chronic fatigue, quality of life and long-term side-effects of chemotherapy in patients treated for non-epithelial ovarian cancer: national case-control protocol study of the GINECO-Vivrovaire rare tumors INCa French network for rare malignant ovarian tumors”. BMC Cancer, 2021, 21 (1), ⟨10.1186/s12885-021-08864-8⟩. ⟨halshs-03428068⟩
Véronique Raimond, Emmanuelle Kaltenbach, Christophe Adam, Sébastien Lazzarotto, Catherine Le Galès, et al.. Challenges raised by the economic evaluation of CAR-T-cell therapies. The review by the French National Authority for Health. Bulletin du Cancer, 2021, ⟨10.1016/j.bulcan.2021.09.001⟩. ⟨halshs-03428067⟩
Valentin Calugaru, Pascal Pommier, Paul Giraud, Philippe Giraud, Eliot Nicolas, et al.. Interpretable Machine Learning Model for Locoregional Relapse Prediction in Oropharyngeal Cancers. Cancers, 2020, 13 (1), pp.57. ⟨10.3390/cancers13010057⟩. ⟨hal-03146371⟩
Mariam El Khal, Lionel Perrier, Julien Carretier, Marina Touillaud, Magalie Hureau, et al.. Coût du programme d’éducation thérapeutique « Mieux manger, mieux bouger à l’aide de l’éducation nutritionnelle » chez les patientes atteintes d’un cancer du sein. Bulletin du Cancer, 2020, 107 (12), pp.1252-1259. ⟨10.1016/j.bulcan.2020.07.003⟩. ⟨halshs-03428053⟩
Lionel Perrier, Aude-Marie Foucaut, Magali Morelle, Marina S. Touillaud, Anne-Sophie Kempf-Lépine, et al.. Cost-effectiveness of an exercise and nutritional intervention versus usual nutritional care during adjuvant treatment for localized breast cancer: the PASAPAS randomized controlled trial. Supportive Care in Cancer, 2020, 28, pp. 2829-2842. ⟨10.1007/s00520-019-05078-4⟩. ⟨halshs-02378666⟩
Séverine Coquerelle, Meryl Darlington, Morgane Michel, Manon Durand, Isabelle Borget, et al.. Impact of Next Generation Sequencing on Clinical Practice in Oncology in France: Better Genetic Profiles for Patients Improve Access to Experimental Treatments. Value in Health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 2020, 23 (7), pp. 898-906. ⟨10.1016/j.jval.2020.03.005⟩. ⟨halshs-02983051⟩
Amina Amadou, Thomas Coudon, Delphine Praud, Pietro Salizzoni, Karen Leffondré, et al.. Chronic Low-Dose Exposure to Xenoestrogen Ambient Air Pollutants and Breast Cancer Risk: XENAIR Protocol for a Case-Control Study Nested Within the French E3N Cohort. JMIR Research Protocols, 2020, 9 (9), pp.e15167. ⟨10.2196/15167⟩. ⟨halshs-03003523⟩
Wilfried Guets, Hareth Al-Janabi, Lionel Perrier. Cost–Utility Analyses of Interventions for Informal Carers: A Systematic and Critical Review. PharmacoEconomics, 2020, 38, pp. 341-356. ⟨10.1007/s40273-019-00874-6⟩. ⟨halshs-02434688⟩
Line Claude, Magali Morelle, Marc-André Mahé, David Pasquier, Pierre Boisselier, et al.. A comparison of two modalities of stereotactic body radiation therapy for peripheral early-stage non-small cell lung cancer: results of a prospective French study. British Journal of Radiology, 2020, 93 (1116), pp.20200256. ⟨10.1259/bjr.20200256⟩. ⟨halshs-03003498⟩
Bruno Laviolle, Olivier Perche, François Gueyffier, Élodie Bégué, Pascal Bilbault, et al.. Apport de la génomique dans la médecine de demain, applications cliniques et enjeux. Thérapie, 2019, 74 (1), pp.1-8. ⟨10.1016/j.therap.2018.11.011⟩. ⟨hal-02056433⟩
Bruno Laviolle, Patrice Denèfle, François Gueyffier, Élodie Bégué, Pascal Bilbault, et al.. The contribution of genomics in the medicine of tomorrow, clinical applications and issues. Thérapie, 2019, 74 (1), pp.9-15. ⟨10.1016/j.therap.2018.11.012⟩. ⟨halshs-02193717⟩
Defourny Noémie, Monten Chris, Grau Cai, Lievens Yolande, Lionel Perrier. Critical review and quality-assessment of cost analyses in radiotherapy: How reliable are the data?. Radiotherapy & Oncology, 2019, 141, pp. 14-26. ⟨10.1016/j.radonc.2019.09.020⟩. ⟨halshs-02378673⟩
Lionel Perrier. Impact financier de l’innovation en oncologie. Innovations & Thérapeutiques en Oncologie, 2019, 5 (2), pp. 66-67. ⟨halshs-02194115⟩
Aude-Marie Foucaut, Magali Morelle, Anne-Sophie Kempf-Lépine, Cédric Baudinet, Renaud Meyrand, et al.. Feasibility of an exercise and nutritional intervention for weight management during adjuvant treatment for localized breast cancer: the PASAPAS randomized controlled trial. Supportive Care in Cancer, 2019, 27 (9), pp. 3449-3461. ⟨10.1007/s00520-019-4658-y⟩. ⟨halshs-02082772⟩
Noémie Defourny, Lionel Perrier, Josep-Maria Borras, Mary Coffey, Julietta Corral, et al.. National costs and resource requirements of external beam radiotherapy: A time-driven activity-based costing model from the ESTRO-HERO project. Radiotherapy & Oncology, 2019, 138, pp. 187-194. ⟨10.1016/j.radonc.2019.06.015⟩. ⟨halshs-02378679⟩
Lionel Perrier, S. Baffert, A. Bertaux, J. Bonastre, N. Costa, et al.. Éditorial. Epidemiology and Public Health = Revue d'Epidémiologie et de Santé Publique, 2018, 66, pp.S63 - S64. ⟨10.1016/j.respe.2018.02.004⟩. ⟨halshs-01819359⟩
Olivia Pérol, Barbara Charbotel, Lionel Perrier, Sandrine Bonnand, Elodie Belladame, et al.. Systematic Screening for Occupational Exposures in Lung Cancer Patients: A Prospective French Cohort. International Journal of Environmental Research and Public Health, 2018, 15 (1), pp.65. ⟨10.3390/ijerph15010065⟩. ⟨halshs-01704517⟩
Jean-Emmanuel Bibault, Magali Morelle, Marius Huguet, Lionel Perrier, Philippe Giraud. In reply to Jean-François Daisne, Sandra Nuyts, Fréderic Duprez and Benoît Bihin. International Journal of Radiation Oncology, Biology, Physics, 2018, 100 (3), pp. 808-809. ⟨halshs-01651501⟩
Olfa Rejeb, Claire Pilet, Sabri Hamana, Xie Xiaolan, Thierry Durand, et al.. Performance and cost evaluation of health information systems using micro-costing and discrete-event simulation. Health Care Management Science, 2018, 21 (2), pp. 204-223. ⟨10.1007/s10729-017-9402-x⟩. ⟨halshs-01526704⟩
Magali Morelle, Morgane Plantier, Benoît Dervaux, Arnaud Pagès, Fanette Deniès, et al.. [Methods for the analysis and treatment of cost data by micro- and gross-costing approaches]. Epidemiology and Public Health = Revue d'Epidémiologie et de Santé Publique, 2018, 66, pp.S101 - S118. ⟨10.1016/j.respe.2018.02.003⟩. ⟨halshs-01784310⟩
Lionel Perrier, Pauline Rascle, Magali Morelle, Maud Toulmonde, Dominique Ranchere Vince, et al.. The cost-saving effect of centralized histological reviews with soft tissue and visceral sarcomas, GIST, and desmoid tumors: The experiences of the pathologists of the French Sarcoma Group. PLoS ONE, 2018, 13 (4), pp.e0193330. ⟨10.1371/journal.pone.0193330⟩. ⟨halshs-01784301⟩
Rajae Touzani, Dede Sika Kossi, Zou Zhaomin, Nathanael Charrier, Sandrine Baffert, et al.. Cost of cancer diagnosis using next-generation sequencing targeted gene panels in routine practice: a nationwide French study (vol 26, pg 314, 2018). European Journal of Human Genetics, 2018, 26 (9), pp.1396-1397. ⟨10.1038/s41431-018-0194-3⟩. ⟨hal-02146886⟩
Marius Huguet, Lionel Perrier, Olivia Bally, David Benayoun, Pierre de Saint Hilaire, et al.. Being Treated In Higher Volume Hospitals Leads To Longer Progression-Free Survival For Epithelial Ovarian Carcinoma Patients in the Rhone-Alpes region of France. BMC Health Services Research, 2018, 18 (3), 11 p. ⟨10.1186/s12913-017-2802-2⟩. ⟨halshs-01670155⟩
Jean-Emmanuel Bibault, Magali Morelle, Marius Huguet, Lionel Perrier, Philippe Giraud. In reply to Tallet et al.. International Journal of Radiation Oncology, Biology, Physics, 2018, 100 (2), pp. 529-530. ⟨halshs-01651499⟩
Patricia Marino, Rajae Touzani, Lionel Perrier, Etienne Rouleau, Dede Sika Kossi, et al.. Cost of cancer diagnosis using next-generation sequencing targeted gene panels in routine practice: a nationwide French study. European Journal of Human Genetics, 2018, 26 (3), pp. 314-323. ⟨10.1038/s41431-017-0081-3⟩. ⟨halshs-01703194⟩
C. Sambou, S. Guillemaut, M. Morelle, A. Achache, A.-G. Le Corroller, et al.. Certification ISO 9001 des Directions de la recherche clinique et de l’innovation : vers une extension du périmètre aux évaluations économiques. Epidemiology and Public Health = Revue d'Epidémiologie et de Santé Publique, 2017, 65 (2), pp.159-167. ⟨10.1016/j.respe.2016.12.026⟩. ⟨inserm-02328562⟩
Morgane Plantier, Nathalie Havet, Thierry Durand, Nicolas Caquot, Camille Amaz, et al.. Does adoption of electronic health records improve the quality of care management in France? Results from the French e-SI (PREPS-SIPS) study. International Journal of Medical Informatics, 2017, 102, pp. 156-165. ⟨10.1016/j.ijmedinf.2017.04.002⟩. ⟨halshs-01619178⟩
Mathilde Penel-Page, Perrine Marec-Berard, Magali Morelle, Amandine Bertrand, Christèle Riberon, et al.. Management of Febrile Neutropenias in Adolescents and Young Adults: A Cost-Minimization Analysis Between Adult Versus Pediatric Units. Journal of Adolescent and Young Adult Oncology, 2017, 6 (4), pp. 542-550. ⟨10.1089/jayao.2017.0035⟩. ⟨halshs-01618890⟩
Mélanie Varin, Barbara Charbotel, Olivia Pérol, Lionel Perrier, Amélie Massardier-Pilonchéry, et al.. Évaluation d’un auto-questionnaire de repérage des expositions professionnelles chez les patients atteints de cancer bronchopulmonaire. Bulletin du Cancer, 2017, 104 (6), pp. 559-564. ⟨10.1016/j.bulcan.2017.03.014⟩. ⟨halshs-01526744⟩
Nathalie Havet, Alexis Penot, Magali Morelle, Lionel Perrier, Barbara Charbotel, et al.. Trends in occupational disparities for exposure to carcinogenic, mutagenic and reprotoxic chemicals in France 2003–10 . European Journal of Public Health, 2017, 27 (3), pp.425-432. ⟨10.1093/eurpub/ckx036⟩. ⟨halshs-01524444⟩
Lionel Perrier, Magali Morelle, Marius Huguet, Sophie Dussart, Philippe Giraud. In Reply to Escande et al. International Journal of Radiation Oncology, Biology, Physics, 2017, 97 (1), pp. 205-208. ⟨halshs-01421123⟩
Morgane Plantier, Nathalie Havet, Thierry Durand, Nicolas Caquot, Camille Amaz, et al.. Does adoption of electronic health records improve organizational performances of hospital surgical units? Results from the French e-SI (PREPS-SIPS) study. International Journal of Medical Informatics, 2017, 98, pp. 47-55. ⟨10.1016/j.ijmedinf.2016.12.002⟩. ⟨halshs-01421101⟩
Jean-Emmanuel Bibault, Sophie Dussart, Pascal Pommier, Magali Morelle, Marius Huguet, et al.. Clinical Outcomes of Several IMRT Techniques for Patients With Head and Neck Cancer: A Propensity Score–Weighted Analysis. International Journal of Radiation Oncology, Biology, Physics, 2017, 99 (4), pp. 929-937. ⟨10.1016/j.ijrobp.2017.06.2456⟩. ⟨halshs-01618896⟩
K. Gnep, T. Lizée, B. Campillo-Gimenez, G. Delpon, S. Droupy, et al.. Toxicité et qualité de vie comparées après curiethérapie par iode 125 et radiothérapie stéréotaxique des cancers prostatiques [Toxicity and quality of life comparison of iodine 125 brachytherapy and stereotactic radiotherapy for prostate cancers]. Cancer/Radiothérapie, 2017, 21 (6-7), pp.478-490. ⟨10.1016/j.canrad.2017.07.043⟩. ⟨hal-01618005⟩
Nathalie Havet, Alexis Penot, Magali Morelle, Lionel Perrier, Barbara Charbotel, et al.. Varied exposure to carcinogenic, mutagenic, and reprotoxic (CMR) chemicals in occupational settings in France. International Archives of Occupational and Environmental Health, 2017, 90 (2), pp. 227-241. ⟨halshs-01446700⟩
Antony Ceraulo, Antoine Ouziel, Emilie Lavergne, Lionel Perrier, Anne-Valérie Decouvelaere, et al.. Percutaneous guided biopsy for diagnosing suspected primary malignant bone tumors in pediatric patients: a safe, accurate, and cost-saving procedure. Pediatric Radiology, 2017, 47 (2), pp. 235-244. ⟨10.1007/s00247-016-3735-3⟩. ⟨halshs-01421085⟩
Anne-Isabelle Poullié, Magali Cognet, Aline Gauthier, Marine Clementz, Sylvain Druais, et al.. Cost-Effectiveness Of Treatments For Mild-To-Moderate Obstructive Sleep Apnea In France. International Journal of Technology Assessment in Health Care, 2016, 32 (1), pp. 1-9. ⟨10.1017/S0266462316000088⟩. ⟨halshs-01327109⟩
Maria-Laura Silva, Lionel Perrier, John Paget, Anne Mosnier, Valérie Buthion, et al.. Influenza vaccination policy-making processes in France and The Netherlands: Framework and determinants. Health Policy, 2016, 120 (3), pp.293-305. ⟨10.1016/j.healthpol.2016.01.005⟩. ⟨halshs-01266374⟩
Lionel Perrier, Magali Morelle, Sophie Dussart, Philippe Giraud. In Reply to Fodor and Di Muzio. International Journal of Radiation Oncology, Biology, Physics, 2016, 96 (5), pp. 1124-1126. ⟨halshs-01421125⟩
J-E Bibault, Magali Morelle, Lionel Perrier, Pascal Pommier, Pierre Boisselier, et al.. Toxicity and efficacy of cetuximab associated with several modalitiesof IMRT for locally advanced head and neck cancer. Cancer/Radiothérapie, 2016, 20 (5), pp. 357-361. ⟨10.1016/j.canrad.2016.05.009⟩. ⟨halshs-01366224⟩
Lionel Perrier, Magali Morelle, Pascal Pommier, Pierre Boisselier, Bernard Coche-Dequeant, et al.. A cost analysis of complex radiotherapy for patients with head and neck cancer. International Journal of Radiation Oncology, Biology, Physics, 2016, 95 (2), pp. 654-662 ⟨10.1016/j.ijrobp.2016.02.013⟩. ⟨halshs-01300834⟩
Maria-Laura Silva, John Paget, Anne Mosnier, Valérie Buthion, Jean Marie Cohen, et al.. Development of Seasonal Influenza Vaccination Recommendations: Relevance and Influence of the Evidence on the Decision-Making Process in France and the Netherlands. Value in Health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 2016, 19 (5), pp.670-679. ⟨10.1016/j.jval.2016.02.006⟩. ⟨halshs-01366179⟩
Noémie Defourny, Peter Dunscombe, Lionel Perrier, Cai Grau, Yolande Lievens. Cost evaluations of radiotherapy: What do we know? An ESTRO-HERO analysis. Radiotherapy & Oncology, 2016, 121 (3), pp. 468-474. ⟨halshs-01421113⟩
Dias Alves, Maria-Laura Silva, Lionel Perrier, John Paget, Anne Mosnier, et al.. “Influenza vaccination policy-making processes in France and The Netherlands: Framework and determinants ». Health Policy, 2016. ⟨hal-02128594⟩
Morgane Plantier, Nathalie Havet, Nicolas Caquot, Pierre Biron, Camille Amaz, et al.. Impact of Electronic Health Records on the Hospital Bed Occupancy Rates in Surgical Units in France: Results from the E-SI (PREPS-SIPS) Study. Athens Journal of Health, 2016, 3 (1), pp. 11-26. ⟨halshs-01237499⟩
Maria-Laura Silva, Lionel Perrier, Jean Marie Cohen, William John Paget, Anne Mosnier, et al.. A literature review to identify factors that determine policies for influenza vaccination. Health Policy, 2015, 119 (6), pp. 697-708. ⟨10.1016/j.healthpol.2015.04.006⟩. ⟨halshs-01156520⟩
Alessandra Buja, Diego Martines, Salvatore Lobello, Lionel Perrier. A cost-consequence analysis of hepatitis B screening in an immigrant population. Annali dell'Istituto Superiore di Sanità, 2015, 51 (5), pp. 327-335. ⟨halshs-01237025⟩
Morgane Plantier, Nathalie Havet, Nicolas Caquot, Pierre Biron, Camille Amaz, et al.. Impact of Electronic Health Records on the Hospital Bed Occupancy Rates in Surgical Units in France: Results from the E-SI (PREPS-SIPS) Study. ATINER’S Conference Paper Series, 2015, HEA2015-1545, 20 p. ⟨halshs-01237556⟩
Lionel Perrier, Alessandra Buja, Giuseppe Mastrangelo, Patrick Sylvestre-Baron, Françoise Ducimetière, et al.. Transferability of health cost evaluation across locations in oncology: cluster and principal component analysis as an explorative tool. BMC Health Services Research, 2014, 14 (1), p. 537. ⟨halshs-01089763⟩
David G. Cox, Stéphane Ragusa, Lionel Pourteau, Lionel Perrier, Suzette Delaloge. Cost-effectiveness of a Genetic Test for Breast Cancer Risk - Letter. Cancer Prevention Research, 2014, ⟨10.1158/1940-6207.CAPR-13-0429⟩. ⟨halshs-00957846⟩
Maria-Laura Silva, Lionel Perrier, Hans-Martin Späth, Nathalie Havet, Jean Marie Cohen, et al.. Economic burden of seasonal influenza B in France during winter 2010-2011. BMC Public Health, 2014, 14 (1), art. 56, 10 p. ⟨10.1186/1471-2458-14-56⟩. ⟨halshs-00954697⟩
Nathalie Havet, Alexis Penot, Magali Morelle, Lionel Perrier, Béatrice Fervers. Inégalités de l'exposition aux produits cancérogènes, mutagènes ou reprotoxiques (CMR) en milieu professionnel en France. Environnement, Risques & Santé, 2014, 13 (4), pp. 336-341. ⟨halshs-01080555⟩
Lionel Perrier, Anne Lefranc, David Pérol, Philippe Quittet, Aline Schmidt-Tanguy, et al.. Cost Effectiveness of Pegfilgrastim Versus Filgrastim After High-Dose Chemotherapy and Autologous Stem Cell Transplantation in Patients with Lymphoma and Myeloma. Applied Health Economics and Health Policy, 2013, 11 (2), pp.129-138. ⟨10.1007/s40258-013-0011-7⟩. ⟨hal-04875619⟩
Lionel Perrier, Anne Lefranc, Philippe Quittet, Philippe Moreau, Carole Siani, et al.. Cost-effectiveness of Pegfilgrastim versus Filgrastim after high-dose chemotherapy and autologous stem cell transplantation in patients with lymphoma and myeloma. Applied Health Economics and Health Policy, 2013, 11 (2), pp. 129-138. ⟨10.1007/s40258-013-0011-7⟩. ⟨halshs-00752571⟩
Lionel Perrier, Magali Morelle, Pascal Pommier. Cost of prostate image-guided radiation therapy: Results of a randomized trial. Radiotherapy & Oncology, 2013, 106 (1), pp.50-58. ⟨10.1016/j.radonc.2012.11.011⟩. ⟨halshs-00799507⟩
Magali Morelle, Lionel Perrier, Pascal Pommier, Frédéric Gomez, F. Millet-Lagarde, et al.. Curiethérapie : valorisation et aspects médico-économiques. Cancer/Radiothérapie, 2013, 17 (2), pp. 178-181. ⟨halshs-00862738⟩
Marina S. Touillaud, Aude-Marie Foucaut, Sophie Berthouze, Eric Reynes, A. S. Kempf-Lépine, et al.. Design of a randomised controlled trial of adapted physical activity during adjuvant treatment for localised breast cancer: the PASAPAS feasibility study. BMJ Open, 2013, 3, pp.e003855. ⟨10.1136/bmjopen-2013-003855⟩. ⟨halshs-00940932⟩
Lionel Perrier, Magali Morelle, Pascal Pommier, Jean-Léon Lagrange, Agnès Laplanche, et al.. Cost of prostate image-guided radiation therapy: results of a randomized trial.. Radiotherapy & Oncology, 2013, 106 (1), pp.50-8. ⟨10.1016/j.radonc.2012.11.011⟩. ⟨hal-00880252⟩
Lionel Perrier, Alessandra Buja, Giuseppe Mastrangelo, Antonella Vecchiato, Paolo Sandonà, et al.. Clinicians' adherence versus non adherence to practice guidelines in the management of patients with sarcoma: a cost-effectiveness assessment in two European regions.. BMC Health Services Research, 2012, 12 (1), pp.82. ⟨10.1186/1472-6963-12-82⟩. ⟨inserm-00711845⟩
Catherine Sebban, Anne Lefranc, Lionel Perrier, Philippe Moreau, Daniel Espinouse, et al.. A randomised phase II study of the efficacy, safety and cost-effectiveness of pegfilgrastim and filgrastim after autologous stem cell transplant for lymphoma and myeloma (PALM study). European Journal of Cancer, 2012, 48 (5), pp. 713-720. ⟨halshs-00680996⟩
Magali Morelle, Lionel Perrier, Pascal Pommier, Renaud de Crevoisier, Agnès Laplanche, et al.. Evaluation économique prospective de la radiothérapie guidée par l'image des cancers de la prostate dans le cadre du programme national de Soutien aux Thérapeutiques Innovantes et Coûteuses. Cancer/Radiothérapie, 2012, 16 (5-6), pp. 444-451. ⟨halshs-00752616⟩
Nora Moumjid, Lionel Perrier, Maria-Laura Silva, Hans-Martin Späth. The use of economic evaluations in health decision-making at the macro level: a literature review. Journal de gestion et d’économie médicales, 2012, 30 (4), pp. 231-251. ⟨halshs-00752572⟩
Nathalie Havet, Magali Morelle, Lionel Perrier, Bertrand Favier, Frédéric Gomez, et al.. Impact of chemotherapy prescriptions and costs on survival in advanced or metastatic NSCLC: a single-institution study using an instrumental variables approach. Journal d'Economie Médicale, 2010, 28 (8), pp. 295-310. ⟨halshs-00667277⟩
Lionel Perrier, Thierry Philip. Apports de l'évaluation économique et de l'analyse d'impact budgétaire pour la décision publique en santé : l'exemple du cancer du sein. Bulletin du Cancer, 2010, 97 (3), pp. 397-402. ⟨halshs-00565785⟩
Christophe Bergeron, Pierre Biron, Jean-Yves Blay, Nicola Cautela, Dominic Cellier, et al.. Costs and compliance with clinical practice guidelines: A pilot study for initial sarcoma treatment. Journal d'Economie Médicale, 2009, 27 (6), pp. 307-327. ⟨halshs-00954975⟩
Lionel Perrier, Pascal Pommier, Marie-Odile Carrère, Patrick Sylvestre-Baron. Transférabilité des évaluations de coûts en santé : analyse des facteurs de variabilité. Revue Economique, 2009, 60 (2), pp. 307-322. ⟨halshs-00451617⟩
Lionel Perrier, S.E. Combs, Thomas Auberger, Luciano Zucca, Ingemar Näslund, et al.. A Decision-making Tool for a Costly Innovative Technology: The Case of Carbon Ion Radiotherapy. Journal d'Economie Médicale, 2008, 25 (7-8), pp. 367-380. ⟨halshs-00353062⟩
Magali Morelle, Lionel Perrier, Hervé Ghesquières, Catherine Sebban, Irène Philip, et al.. The impact of CD34+ cell dose on the cost of HDT with PBSC transplantation in lymphomia. Journal dÉconomie Médicale, 2007, 25 (1), pp.3-15. ⟨halshs-00159806⟩
Lionel Perrier, Thierry Philip. Trajectoires optimales des patients évoluant vers la dépendance. Sante et Systemique, 2005, 8 (3 - 4), pp.73-86. ⟨halshs-00157163⟩
Lionel Perrier, Karima Nessah, Magali Morelle, Hervé Mignotte, Marie-Odile Carrère, et al.. Cost comparison of two surgical strategies in the treatment of breast cancer: Sentinel lymph node biopsy versus axillary lymph node dissection. International Journal of Technology Assessment in Health Care, 2004, 20 (4), pp. 449-454. ⟨halshs-00335472⟩
Pascal Pommier, Luciano Zucca, Ingemar Näslund, Thomas Auberger, Stephanie E. Combs, et al.. Light ion facility projects in Europe: methodological aspects for the calculation of the treatment cost per protocol. Radiotherapy & Oncology, 2004, 73 (Supplement 2), pp.183-185. ⟨10.1016/S0167-8140(04)80045-8⟩. ⟨halshs-00156706⟩
Lionel Perrier, Catherine Sebban, Irène Philip, Baudouin Standaert, Magali Morelle, et al.. Vers une nécessaire harmonisation des évaluations de coûts en santé. L'exemple des intensifications thérapeutiques avec autogreffes de cellules souches du sang périphérique en France. Epidemiology and Public Health = Revue d'Epidémiologie et de Santé Publique, 2002, 50 (4), pp. 393-403. ⟨halshs-00335619⟩
Béatrice Rey, Frédéric Chauvin, Lionel Perrier. Les apports des concepts économiques "d'équipe" et de "groupe" pour l'évaluation des réseaux de soins. Journal d'Economie Médicale, 2001, 19 (5-6), pp.381-389. ⟨halshs-03353413⟩
CV
TEACHING ▼
- MSc in Health Management & Data Intelligence, Mines Saint-Etienne & EM Lyon Business School
- Parcours post-Master et post-Doctorat, Université Catholique de Lyon
- MSc Management éthique des innovations biotechnologiques, Université Catholique de Lyon
- Master 2 Risques et Environnement, Ecole Centrale de Lyon
- D.U. Infirmier en hygiène, Université Jean Monnet, Saint-Etienne
INSTITUTIONAL RESPONSABILITIES ▼
- Member of the selection committees for grants Programme de Recherche Médico-Economique (PRME), French Ministry of Health (2013 – …) and Programme Hospitalier de Recherche Clinique National (PHRC-N), French Ministry of Health (2024 – …)
- Member of the Economic and Public Health Evaluation Committee (CEESP), the French National Authority for Health -HAS- (2015 – 2024)
- Member of the national Working groups Evaluation and validation of new indications for access to genomic diagnosis and Health economics, Plan France Médecine Génomique 2025
- Member of the Board Organisation of European Cancer Institutes (OECI) Health – Economics Working Group (2019 – …)
- Member of the Ethics Focus Group, Leon Berard Cancer Centre, Lyon, France (2018 – …)
- Member of the several Abstract Review Committees: the International Society For Pharmacoeconomics and Outcomes Research (ISPOR), the international Health Economics Association (iHEA), the European SocieTy for Radiotherapy and Oncology ESTRO)
EXPERTISE ▼
- Expert advisor for grants: Programme Hospitalier de Recherche Infirmière et Paramédicale (PHRIP), Programme de Recherche sur la Performance du Système des Soins (PREPS), French Ministry of Health; Generic Call for Proposals 2023, French National Research Agency (ANR)
- Lecturer: Ecole Centrale de Lyon (2014 – …), Mines Saint-Etienne & EM Lyon Business School (2019 – …), UCLy (Catholic University of Lyon) (2019 – …), University of Lyon (2007 – …), University of Saint-Etienne (2019 – …), Institut d’Etudes Politiques de Grenoble (2019 – 2022)
- Director/co-director of PhD theses: Wilfried Guets “Modélisation de l’aide informelle : approches économiques et applications au dispositif innovant d’accompagnement et de répit des aidants de la métropole de Lyon“ (defended in 2021); Marius Huguet, “Traitement du biais de sélection, estimation de l’effet causal et modélisation microéconomique” (defended in 2020); Noémie Defourny “The cost of Radiotherapy in Europe: what does it cost, and how can these data be used to support innovation in European radiotherapy practice?“ (defended in 2019); Maria Laura Silva “The role of the economic evaluations in health decision making: an application to influenza vaccination” (defended in 2016)
- Participation as referee / external examiner of numerous PhD theses and HDR defense
- Peer review: European Journal of Cancer, Pharmacoeconomics & Outcomes Research, Social Science and Medicine, The International Journal for Quality in Health Care, Value in Health, etc.